Helicobacter pylori str. UM163

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain UM163 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives at an optimal temperature of 37.0°C, indicating its adaptation to the human body, which serves as its primary habitat. As a host-associated microbe, H. pylori UM163 is intimately linked to the gastric environment, where it may influence various physiological processes. The microaerophilic nature of this strain suggests that it requires reduced oxygen levels for growth, which aligns with its gastric niche, where oxygen concentrations are lower than in the external environment. This adaptation could be crucial for its survival and function within the host's stomach, allowing it to evade the immune response while colonizing the mucosal lining. Understanding the specific traits of H. pylori UM163 provides insights into its ecological role in the human gastrointestinal tract. Its ability to thrive in a microaerophilic environment highlights the unique adaptations that bacteria can develop to exploit specific niches within host organisms. Further exploration of its interactions with the host and the implications for gastric health could reveal important aspects of microbial ecology and human health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. UM163

Accession NumberLFJR00000000.1

Gene Summary

Adenine Count

510168 bp

Thymine Count

508811 bp

Guanine Count

318516 bp

Cytosine Count

318824 bp

Genome Length

1656397 bp

Protein-coding Genes

1487 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
udp-3-o-(3-hydroxymyristoyl) glucosamine n-acyltransferaseAK968_00050Q9ZM50-9899 - 1078632727.1
septum formation inhibitorAK968_00055B6JKX0-10783 - 1137022411.4
hypothetical proteinAK968_00060Not Available-11373 - 1269550121.4
hypothetical proteinAK968_00065Not Available-12705 - 1364335543.8
hypothetical proteinAK968_00070Not Available-13652 - 1450632255.1
hypothetical proteinAK968_00075Not Available-14496 - 1521827335.3
3-methyl-2-oxobutanoate hydroxymethyltransferaseAK968_00080B2USM4+15368 - 1618029823.4
atp-dependent dna helicase ruvbAK968_00085B2USM3+16181 - 1719137269.4
preprotein translocaseAK968_00090Q1CUB8+17259 - 1774118371.7
preprotein translocase subunit tatcAK968_00095Q9ZM59+17734 - 1849528160.9

Displaying genes 11 – 20 of 1529 in total

Pathways

26 pathways

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0011787(S)-2-hydroxymethylglutarateC6H8O5Chemical structure of (S)-2-hydroxymethylglutarateNot available
Average160.126Da
Monoisotopic160.038270517Da
BASm0012597(6R)-10-formyltetrahydrofolateC20H21N7O7Chemical structure of (6R)-10-formyltetrahydrofolateNot available
Average471.431Da
Monoisotopic471.151343204Da

Displaying 91–92 of 92 metabolites