Helicobacter pylori str. UM163

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain UM163 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives at an optimal temperature of 37.0°C, indicating its adaptation to the human body, which serves as its primary habitat. As a host-associated microbe, H. pylori UM163 is intimately linked to the gastric environment, where it may influence various physiological processes. The microaerophilic nature of this strain suggests that it requires reduced oxygen levels for growth, which aligns with its gastric niche, where oxygen concentrations are lower than in the external environment. This adaptation could be crucial for its survival and function within the host's stomach, allowing it to evade the immune response while colonizing the mucosal lining. Understanding the specific traits of H. pylori UM163 provides insights into its ecological role in the human gastrointestinal tract. Its ability to thrive in a microaerophilic environment highlights the unique adaptations that bacteria can develop to exploit specific niches within host organisms. Further exploration of its interactions with the host and the implications for gastric health could reveal important aspects of microbial ecology and human health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. UM163

Accession NumberLFJR00000000.1

Gene Summary

Adenine Count

510168 bp

Thymine Count

508811 bp

Guanine Count

318516 bp

Cytosine Count

318824 bp

Genome Length

1656397 bp

Protein-coding Genes

1487 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinAK968_07735Not Available-1595247 - 159583722483.1
cysteine desulfuraseAK968_07740Not Available-1595863 - 159718548467.8
hypothetical proteinAK968_07745P64383-1597204 - 159751811841.5
phenylalanyl-trna synthetase subunit alphaAK968_07750B2UUF7+1597599 - 159858537844.5
phenylalanyl-trna synthetase subunit betaAK968_07755P56145+1598585 - 160087985045.5
3-phosphoshikimate 1-carboxyvinyltransferaseAK968_07760B5Z850+1600895 - 160218447274.6
4-hydroxy-3-methylbut-2-enyl diphosphate reductaseAK968_07765B2UUG0+1602174 - 160299830875.6
30s ribosomal protein s1AK968_07770P56008+1603119 - 160477762340.5
hypothetical proteinAK968_07775Not Available+1604806 - 160534521180.9
3-phosphoglycerate dehydrogenaseAK968_07780O27051+1605361 - 160693557789.4

Displaying genes 1471 – 1480 of 1529 in total

Pathways

26 pathways

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 92 metabolites