Helicobacter pylori str. UM131

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain UM131 is a Gram-negative bacterium characterized by its spiral shape and the tendency to exist as single cells. This microbe thrives in a microaerophilic environment, indicating that it requires reduced levels of oxygen for optimal growth, which aligns with its natural habitat within the host. The optimal temperature for H. pylori UM131 is approximately 37.0°C, reflecting its adaptation to the human body, where it can colonize the gastric mucosa. As a member of the Helicobacter genus, UM131 is associated with the gastric environment, where it may play a role in various host-associated biological processes. The microorganism’s unique spiral morphology may facilitate its motility within the viscous environment of the stomach, potentially influencing its colonization capabilities. The presence of H. pylori in the gastric tract underscores its ecological niche as a persistent inhabitant of the human stomach, where it can interact with the host's immune system and contribute to the overall microbiome. Understanding the traits of H. pylori UM131 can provide insights into its physiological adaptations, which may have implications for its role in gastrointestinal health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. UM131

Accession NumberLFBZ00000000.1

Gene Summary

Adenine Count

489391 bp

Thymine Count

482592 bp

Guanine Count

312151 bp

Cytosine Count

313318 bp

Genome Length

1597529 bp

Protein-coding Genes

1442 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+72 - 189Not Available
hypothetical proteinAC784_00005Not Available+95 - 43612420.9
membrane proteinAC784_00010Not Available+458 - 6587326.3
membrane proteinAC784_00015Not Available-889 - 228953586.6
membrane proteinAC784_00020Not Available-2362 - 394859738.1
catalaseAC784_00025Not Available+4236 - 518035926.6
dna methyltransferaseAC784_00035P50192-6152 - 720739597.0
restriction endonucleaseAC784_00045Not Available-7924 - 880534099.5
gtp-binding proteinAC784_00050O25225-8868 - 1066766738.5
glycosyltransferase 9 family proteinAC784_00055Not Available-10713 - 1156133273.1

Displaying genes 1 – 10 of 1484 in total

Pathways

26 pathways

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm00044322,4-diacetamido-2,4,6-trideoxy-beta-L-altroseC10H18N2O5Chemical structure of 2,4-diacetamido-2,4,6-trideoxy-beta-L-altroseNot available
Average246.263Da
Monoisotopic246.1215717Da
BASm0004444UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamineC17H27N4O15P2Chemical structure of UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamineNot available
Average589.364Da
Monoisotopic589.0953638Da
BASm0004488CMP-pseudaminateC22H32N5O15PChemical structure of CMP-pseudaminateNot available
Average637.493Da
Monoisotopic637.1643495Da
BASm0004531(6S)-NADHXC21H29N7O15P2Chemical structure of (6S)-NADHXNot available
Average681.446Da
Monoisotopic681.1207844Da
BASm0004532(6R)-NADHXC21H29N7O15P2Chemical structure of (6R)-NADHXNot available
Average681.446Da
Monoisotopic681.1207844Da
BASm0004533(6S)-NADPHXC21H28N7O18P3Chemical structure of (6S)-NADPHXNot available
Average759.409Da
Monoisotopic759.0725624Da
BASm0004534(6R)-NADPHXC21H28N7O18P3Chemical structure of (6R)-NADPHXNot available
Average759.409Da
Monoisotopic759.072562403Da
BASm0004565cyclic dehypoxanthinylfutalosinateC14H13O7Chemical structure of cyclic dehypoxanthinylfutalosinateNot available
Average293.252Da
Monoisotopic293.0666763Da
BASm00045736-amino-6-deoxyfutalosineC19H18N5O6Chemical structure of 6-amino-6-deoxyfutalosineNot available
Average412.383Da
Monoisotopic412.1262569Da
BASm0004720carboxynorspermidineC7H19N3O2Chemical structure of carboxynorspermidineNot available
Average177.247Da
Monoisotopic177.1466297Da

Displaying 61–70 of 94 metabolites