Helicobacter pylori str. UM131

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain UM131 is a Gram-negative bacterium characterized by its spiral shape and the tendency to exist as single cells. This microbe thrives in a microaerophilic environment, indicating that it requires reduced levels of oxygen for optimal growth, which aligns with its natural habitat within the host. The optimal temperature for H. pylori UM131 is approximately 37.0°C, reflecting its adaptation to the human body, where it can colonize the gastric mucosa. As a member of the Helicobacter genus, UM131 is associated with the gastric environment, where it may play a role in various host-associated biological processes. The microorganism’s unique spiral morphology may facilitate its motility within the viscous environment of the stomach, potentially influencing its colonization capabilities. The presence of H. pylori in the gastric tract underscores its ecological niche as a persistent inhabitant of the human stomach, where it can interact with the host's immune system and contribute to the overall microbiome. Understanding the traits of H. pylori UM131 can provide insights into its physiological adaptations, which may have implications for its role in gastrointestinal health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. UM131

Accession NumberLFBZ00000000.1

Gene Summary

Adenine Count

489391 bp

Thymine Count

482592 bp

Guanine Count

312151 bp

Cytosine Count

313318 bp

Genome Length

1597529 bp

Protein-coding Genes

1442 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+72 - 189Not Available
hypothetical proteinAC784_00005Not Available+95 - 43612420.9
membrane proteinAC784_00010Not Available+458 - 6587326.3
membrane proteinAC784_00015Not Available-889 - 228953586.6
membrane proteinAC784_00020Not Available-2362 - 394859738.1
catalaseAC784_00025Not Available+4236 - 518035926.6
dna methyltransferaseAC784_00035P50192-6152 - 720739597.0
restriction endonucleaseAC784_00045Not Available-7924 - 880534099.5
gtp-binding proteinAC784_00050O25225-8868 - 1066766738.5
glycosyltransferase 9 family proteinAC784_00055Not Available-10713 - 1156133273.1

Displaying genes 1 – 10 of 1484 in total

Pathways

26 pathways

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0010884(7R,8S)-7,8-diammoniononanoateC9H21N2O2Chemical structure of (7R,8S)-7,8-diammoniononanoateNot available
Average189.278Da
Monoisotopic189.1597543Da
BASm0010887(4R,5S)-dethiobiotinC10H18N2O3Chemical structure of (4R,5S)-dethiobiotin533-48-2
Average214.2615Da
Monoisotopic214.1317425Da
BASm0011787(S)-2-hydroxymethylglutarateC6H8O5Chemical structure of (S)-2-hydroxymethylglutarateNot available
Average160.126Da
Monoisotopic160.038270517Da
BASm0012597(6R)-10-formyltetrahydrofolateC20H21N7O7Chemical structure of (6R)-10-formyltetrahydrofolateNot available
Average471.431Da
Monoisotopic471.151343204Da

Displaying 91–94 of 94 metabolites