Helicobacter pylori str. UM131

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain UM131 is a Gram-negative bacterium characterized by its spiral shape and the tendency to exist as single cells. This microbe thrives in a microaerophilic environment, indicating that it requires reduced levels of oxygen for optimal growth, which aligns with its natural habitat within the host. The optimal temperature for H. pylori UM131 is approximately 37.0°C, reflecting its adaptation to the human body, where it can colonize the gastric mucosa. As a member of the Helicobacter genus, UM131 is associated with the gastric environment, where it may play a role in various host-associated biological processes. The microorganism’s unique spiral morphology may facilitate its motility within the viscous environment of the stomach, potentially influencing its colonization capabilities. The presence of H. pylori in the gastric tract underscores its ecological niche as a persistent inhabitant of the human stomach, where it can interact with the host's immune system and contribute to the overall microbiome. Understanding the traits of H. pylori UM131 can provide insights into its physiological adaptations, which may have implications for its role in gastrointestinal health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. UM131

Accession NumberLFBZ00000000.1

Gene Summary

Adenine Count

489391 bp

Thymine Count

482592 bp

Guanine Count

312151 bp

Cytosine Count

313318 bp

Genome Length

1597529 bp

Protein-coding Genes

1442 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+72 - 189Not Available
hypothetical proteinAC784_00005Not Available+95 - 43612420.9
membrane proteinAC784_00010Not Available+458 - 6587326.3
membrane proteinAC784_00015Not Available-889 - 228953586.6
membrane proteinAC784_00020Not Available-2362 - 394859738.1
catalaseAC784_00025Not Available+4236 - 518035926.6
dna methyltransferaseAC784_00035P50192-6152 - 720739597.0
restriction endonucleaseAC784_00045Not Available-7924 - 880534099.5
gtp-binding proteinAC784_00050O25225-8868 - 1066766738.5
glycosyltransferase 9 family proteinAC784_00055Not Available-10713 - 1156133273.1

Displaying genes 1 – 10 of 1484 in total

Pathways

26 pathways

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 94 metabolites