Helicobacter pylori str. 29CaP

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 29CaP is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, indicating its adaptation to host-associated environments, likely within the gastric mucosa of mammals. The microaerophilic nature of H. pylori str. 29CaP suggests that it requires low levels of oxygen for growth, which is consistent with its ecological niche in the acidic environment of the stomach, where oxygen levels are typically reduced. The specific morphology of H. pylori str. 29CaP, combined with its physiological requirements, highlights its specialized adaptations for survival in a highly competitive and hostile habitat. This strain's characteristics may contribute to its ability to persist in the gastric environment, where it can interact with the host's immune response and microbiome. Understanding the traits of H. pylori str. 29CaP can provide insights into its role in gastric health and disease, as well as its ecological dynamics within the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 29CaP

Accession NumberNZ_CP012905.1

Gene Summary

Adenine Count

491352 bp

Thymine Count

499248 bp

Guanine Count

311836 bp

Cytosine Count

321991 bp

Genome Length

1624441 bp

Protein-coding Genes

1511 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
transcription antitermination factor nusbAPV63_RS00005B5Z6D7-89 - 50515520.0
6,7-dimethyl-8-ribityllumazine synthaseAPV63_RS00010B6JPA1-507 - 97716970.7
3-deoxy-8-phosphooctulonate synthaseAPV63_RS00015Q9ZN55-987 - 181730363.7
carbonic anhydraseAPV63_RS00020Q9ZN54-1804 - 246925894.0
orotidine-5'-phosphate decarboxylaseAPV63_RS00025B2UW09+2592 - 327525396.2
pantoate--beta-alanine ligaseAPV63_RS00030B6JPA5+3276 - 410631180.2
Trna-gluNot AvailableNot Available+4120 - 4195Not Available
Trna-aspNot AvailableNot Available+4255 - 4331Not Available
Trna-valNot AvailableNot Available+4372 - 4447Not Available
Trna-gluNot AvailableNot Available+4488 - 4562Not Available

Displaying genes 1 – 10 of 1556 in total

Pathways

26 pathways

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0004722carboxyspermidineC8H21N3O2Chemical structure of carboxyspermidineNot available
Average191.274Da
Monoisotopic191.1622798Da
BASm0004925UDP-N-acetyl-alpha-D-muramateC20H28N3O19P2Chemical structure of UDP-N-acetyl-alpha-D-muramateNot available
Average676.395Da
Monoisotopic676.080870429Da
BASm0005091(4S)-4-hydroxy-2-oxoglutarateC5H4O6Chemical structure of (4S)-4-hydroxy-2-oxoglutarateNot available
Average160.082Da
Monoisotopic160.001885009Da
BASm0005278GDP-4-dehydro-3,6-dideoxy-alpha-D-mannoseC16H21N5O14P2Chemical structure of GDP-4-dehydro-3,6-dideoxy-alpha-D-mannoseNot available
Average569.314Da
Monoisotopic569.0571215Da
BASm0005279GDP-beta-L-colitoseC16H23N5O14P2Chemical structure of GDP-beta-L-colitoseNot available
Average571.33Da
Monoisotopic571.0727716Da
BASm00060353-[(1-carboxyvinyl)-oxy]benzoateC10H6O5Chemical structure of 3-[(1-carboxyvinyl)-oxy]benzoateNot available
Average206.154Da
Monoisotopic206.0226205Da
BASm0007001UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamateC28H39N5O23P2Chemical structure of UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamateNot available
Average875.582Da
Monoisotopic875.1533009Da
BASm0007003UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioateC35H51N7O26P2Chemical structure of UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioateNot available
Average1047.7583Da
Monoisotopic1047.235898Da
BASm0007367(6S)-5,6,7,8-tetrahydropteroateC14H15N6O3Chemical structure of (6S)-5,6,7,8-tetrahydropteroateNot available
Average315.314Da
Monoisotopic315.1211119Da
BASm00074603-deoxy-alpha-D-manno-2-octulosonate-8-phosphateC8H12O11PChemical structure of 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphateNot available
Average315.148Da
Monoisotopic315.0133689Da

Displaying 71–80 of 94 metabolites