Helicobacter pylori str. 29CaP

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 29CaP is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, indicating its adaptation to host-associated environments, likely within the gastric mucosa of mammals. The microaerophilic nature of H. pylori str. 29CaP suggests that it requires low levels of oxygen for growth, which is consistent with its ecological niche in the acidic environment of the stomach, where oxygen levels are typically reduced. The specific morphology of H. pylori str. 29CaP, combined with its physiological requirements, highlights its specialized adaptations for survival in a highly competitive and hostile habitat. This strain's characteristics may contribute to its ability to persist in the gastric environment, where it can interact with the host's immune response and microbiome. Understanding the traits of H. pylori str. 29CaP can provide insights into its role in gastric health and disease, as well as its ecological dynamics within the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 29CaP

Accession NumberNZ_CP012905.1

Gene Summary

Adenine Count

491352 bp

Thymine Count

499248 bp

Guanine Count

311836 bp

Cytosine Count

321991 bp

Genome Length

1624441 bp

Protein-coding Genes

1511 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
transcription antitermination factor nusbAPV63_RS00005B5Z6D7-89 - 50515520.0
6,7-dimethyl-8-ribityllumazine synthaseAPV63_RS00010B6JPA1-507 - 97716970.7
3-deoxy-8-phosphooctulonate synthaseAPV63_RS00015Q9ZN55-987 - 181730363.7
carbonic anhydraseAPV63_RS00020Q9ZN54-1804 - 246925894.0
orotidine-5'-phosphate decarboxylaseAPV63_RS00025B2UW09+2592 - 327525396.2
pantoate--beta-alanine ligaseAPV63_RS00030B6JPA5+3276 - 410631180.2
Trna-gluNot AvailableNot Available+4120 - 4195Not Available
Trna-aspNot AvailableNot Available+4255 - 4331Not Available
Trna-valNot AvailableNot Available+4372 - 4447Not Available
Trna-gluNot AvailableNot Available+4488 - 4562Not Available

Displaying genes 1 – 10 of 1556 in total

Pathways

26 pathways

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm00044322,4-diacetamido-2,4,6-trideoxy-beta-L-altroseC10H18N2O5Chemical structure of 2,4-diacetamido-2,4,6-trideoxy-beta-L-altroseNot available
Average246.263Da
Monoisotopic246.1215717Da
BASm0004444UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamineC17H27N4O15P2Chemical structure of UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamineNot available
Average589.364Da
Monoisotopic589.0953638Da
BASm0004488CMP-pseudaminateC22H32N5O15PChemical structure of CMP-pseudaminateNot available
Average637.493Da
Monoisotopic637.1643495Da
BASm0004531(6S)-NADHXC21H29N7O15P2Chemical structure of (6S)-NADHXNot available
Average681.446Da
Monoisotopic681.1207844Da
BASm0004532(6R)-NADHXC21H29N7O15P2Chemical structure of (6R)-NADHXNot available
Average681.446Da
Monoisotopic681.1207844Da
BASm0004533(6S)-NADPHXC21H28N7O18P3Chemical structure of (6S)-NADPHXNot available
Average759.409Da
Monoisotopic759.0725624Da
BASm0004534(6R)-NADPHXC21H28N7O18P3Chemical structure of (6R)-NADPHXNot available
Average759.409Da
Monoisotopic759.072562403Da
BASm0004565cyclic dehypoxanthinylfutalosinateC14H13O7Chemical structure of cyclic dehypoxanthinylfutalosinateNot available
Average293.252Da
Monoisotopic293.0666763Da
BASm00045736-amino-6-deoxyfutalosineC19H18N5O6Chemical structure of 6-amino-6-deoxyfutalosineNot available
Average412.383Da
Monoisotopic412.1262569Da
BASm0004720carboxynorspermidineC7H19N3O2Chemical structure of carboxynorspermidineNot available
Average177.247Da
Monoisotopic177.1466297Da

Displaying 61–70 of 94 metabolites