Helicobacter pylori str. 29CaP

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 29CaP is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, indicating its adaptation to host-associated environments, likely within the gastric mucosa of mammals. The microaerophilic nature of H. pylori str. 29CaP suggests that it requires low levels of oxygen for growth, which is consistent with its ecological niche in the acidic environment of the stomach, where oxygen levels are typically reduced. The specific morphology of H. pylori str. 29CaP, combined with its physiological requirements, highlights its specialized adaptations for survival in a highly competitive and hostile habitat. This strain's characteristics may contribute to its ability to persist in the gastric environment, where it can interact with the host's immune response and microbiome. Understanding the traits of H. pylori str. 29CaP can provide insights into its role in gastric health and disease, as well as its ecological dynamics within the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 29CaP

Accession NumberNZ_CP012905.1

Gene Summary

Adenine Count

491352 bp

Thymine Count

499248 bp

Guanine Count

311836 bp

Cytosine Count

321991 bp

Genome Length

1624441 bp

Protein-coding Genes

1511 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
transcription antitermination factor nusbAPV63_RS00005B5Z6D7-89 - 50515520.0
6,7-dimethyl-8-ribityllumazine synthaseAPV63_RS00010B6JPA1-507 - 97716970.7
3-deoxy-8-phosphooctulonate synthaseAPV63_RS00015Q9ZN55-987 - 181730363.7
carbonic anhydraseAPV63_RS00020Q9ZN54-1804 - 246925894.0
orotidine-5'-phosphate decarboxylaseAPV63_RS00025B2UW09+2592 - 327525396.2
pantoate--beta-alanine ligaseAPV63_RS00030B6JPA5+3276 - 410631180.2
Trna-gluNot AvailableNot Available+4120 - 4195Not Available
Trna-aspNot AvailableNot Available+4255 - 4331Not Available
Trna-valNot AvailableNot Available+4372 - 4447Not Available
Trna-gluNot AvailableNot Available+4488 - 4562Not Available

Displaying genes 1 – 10 of 1556 in total

Pathways

26 pathways

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm00034704-(phosphooxy)-L-threonineC4H8NO7PChemical structure of 4-(phosphooxy)-L-threonineNot available
Average213.083Da
Monoisotopic213.0049358Da
BASm00034715-amino-6-(5-phospho-D-ribosylamino)uracilC9H13N4O9PChemical structure of 5-amino-6-(5-phospho-D-ribosylamino)uracilNot available
Average352.197Da
Monoisotopic352.0431122Da
BASm0003491(2S)-2-acetolactateC5H7O4Chemical structure of (2S)-2-acetolactateNot available
Average131.108Da
Monoisotopic131.0349823Da
BASm00034972-C-methyl-D-erythritol 2,4-cyclic diphosphateC5H10O9P2Chemical structure of 2-C-methyl-D-erythritol 2,4-cyclic diphosphate143488-44-2
Average276.075Da
Monoisotopic275.9800049Da
BASm0003686(2E,6E,10E)-geranylgeranyl diphosphateC20H33O7P2Chemical structure of (2E,6E,10E)-geranylgeranyl diphosphateNot available
Average447.426Da
Monoisotopic447.171798138Da
BASm0003701L-methionine (S)-S-oxideC5H11NO3SChemical structure of L-methionine (S)-S-oxide62697-73-8
Average165.21Da
Monoisotopic165.045964392Da
BASm0003761dehypoxanthine futalosineC14H16O7Chemical structure of dehypoxanthine futalosineNot available
Average296.275Da
Monoisotopic296.0896029Da
BASm0003763(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphateC11H12NO6PChemical structure of (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphateNot available
Average285.1898Da
Monoisotopic285.0402236Da
BASm0003841N-[(R)-4-phosphopantothenoyl]-L-cysteineC12H20N2O9PSChemical structure of N-[(R)-4-phosphopantothenoyl]-L-cysteineNot available
Average399.33Da
Monoisotopic399.064359144Da
BASm0003896ADP-D-glycero-beta-D-manno-heptoseC17H25N5O16P2Chemical structure of ADP-D-glycero-beta-D-manno-heptoseNot available
Average617.355Da
Monoisotopic617.078250901Da

Displaying 41–50 of 94 metabolites