Helicobacter pylori str. 29CaP

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 29CaP is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, indicating its adaptation to host-associated environments, likely within the gastric mucosa of mammals. The microaerophilic nature of H. pylori str. 29CaP suggests that it requires low levels of oxygen for growth, which is consistent with its ecological niche in the acidic environment of the stomach, where oxygen levels are typically reduced. The specific morphology of H. pylori str. 29CaP, combined with its physiological requirements, highlights its specialized adaptations for survival in a highly competitive and hostile habitat. This strain's characteristics may contribute to its ability to persist in the gastric environment, where it can interact with the host's immune response and microbiome. Understanding the traits of H. pylori str. 29CaP can provide insights into its role in gastric health and disease, as well as its ecological dynamics within the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 29CaP

Accession NumberNZ_CP012905.1

Gene Summary

Adenine Count

491352 bp

Thymine Count

499248 bp

Guanine Count

311836 bp

Cytosine Count

321991 bp

Genome Length

1624441 bp

Protein-coding Genes

1511 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Ncrna_class:srp_rnaNot AvailableNot Available+16755 - 16852Not Available
cog3014 family proteinAPV63_RS00110Not Available+17026 - 1836650963.6
chemotaxis protein chev1APV63_RS00115O24864+18466 - 1943136576.2
carboxynorspermidine decarboxylaseAPV63_RS00120A8FNH9+19428 - 2064545812.0
lipid a 1-phosphatase lpxeAPV63_RS00125Q9ZN40-20642 - 2120220606.1
phosphoethanolamine--lipid a transferase eptaAPV63_RS00130O24867-21252 - 2281759163.2
saba family sialic acid-binding adhesinAPV63_RS00135Not Available-23392 - 2546775236.9
citrate synthaseAPV63_RS00140Q9ZN37-26112 - 2739248423.2
isocitrate dehydrogenase (nadp(+))APV63_RS00145Q9ZN36+27591 - 2886847462.8
duf1523 family proteinAPV63_RS00150P43999+28936 - 2946320224.7

Displaying genes 21 – 30 of 1556 in total

Pathways

26 pathways

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm00074613-deoxy-alpha-D-manno-oct-2-ulosonateC8H13O8Chemical structure of 3-deoxy-alpha-D-manno-oct-2-ulosonateNot available
Average237.185Da
Monoisotopic237.061591Da
BASm0007625prenyl-FMNH2C22H29N4O9PChemical structure of prenyl-FMNH2Not available
Average524.468Da
Monoisotopic524.1683127Da
BASm00077112''-O-succinyl-ADP-D-riboseC19H24N5O17P2Chemical structure of 2''-O-succinyl-ADP-D-riboseNot available
Average656.368Da
Monoisotopic656.065889069Da
BASm0007732dimethylallyl phosphateC5H9O4PChemical structure of dimethylallyl phosphateNot available
Average164.098Da
Monoisotopic164.0249429Da
BASm0008099(2E)-4-hydroxy-3-methylbut-2-enyl diphosphateC5H9O8P2Chemical structure of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphateNot available
Average259.0677Da
Monoisotopic258.9772653Da
BASm0008132(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphateC10H12N5O14P3Chemical structure of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphateNot available
Average519.15Da
Monoisotopic518.9615554Da
BASm0008580carboxy-S-adenosyl-L-methionineC16H22N6O7SChemical structure of carboxy-S-adenosyl-L-methionineNot available
Average442.45Da
Monoisotopic442.1270682Da
BASm0008715biliverdin IXdeltaC33H33N4O6Chemical structure of biliverdin IXdeltaNot available
Average581.65Da
Monoisotopic581.2405584Da
BASm0010316N(1)-(5-phospho-beta-D-ribosyl)glycinamideC7H14N2O8PChemical structure of N(1)-(5-phospho-beta-D-ribosyl)glycinamideNot available
Average285.169Da
Monoisotopic285.049326Da
BASm00107383-phosphoshikimateC7H8O8PChemical structure of 3-phosphoshikimateNot available
Average251.108Da
Monoisotopic250.997324955Da

Displaying 81–90 of 94 metabolites