Helicobacter pylori str. 29CaP

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 29CaP is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, indicating its adaptation to host-associated environments, likely within the gastric mucosa of mammals. The microaerophilic nature of H. pylori str. 29CaP suggests that it requires low levels of oxygen for growth, which is consistent with its ecological niche in the acidic environment of the stomach, where oxygen levels are typically reduced. The specific morphology of H. pylori str. 29CaP, combined with its physiological requirements, highlights its specialized adaptations for survival in a highly competitive and hostile habitat. This strain's characteristics may contribute to its ability to persist in the gastric environment, where it can interact with the host's immune response and microbiome. Understanding the traits of H. pylori str. 29CaP can provide insights into its role in gastric health and disease, as well as its ecological dynamics within the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 29CaP

Accession NumberNZ_CP012905.1

Gene Summary

Adenine Count

491352 bp

Thymine Count

499248 bp

Guanine Count

311836 bp

Cytosine Count

321991 bp

Genome Length

1624441 bp

Protein-coding Genes

1511 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Ncrna_class:srp_rnaNot AvailableNot Available+16755 - 16852Not Available
cog3014 family proteinAPV63_RS00110Not Available+17026 - 1836650963.6
chemotaxis protein chev1APV63_RS00115O24864+18466 - 1943136576.2
carboxynorspermidine decarboxylaseAPV63_RS00120A8FNH9+19428 - 2064545812.0
lipid a 1-phosphatase lpxeAPV63_RS00125Q9ZN40-20642 - 2120220606.1
phosphoethanolamine--lipid a transferase eptaAPV63_RS00130O24867-21252 - 2281759163.2
saba family sialic acid-binding adhesinAPV63_RS00135Not Available-23392 - 2546775236.9
citrate synthaseAPV63_RS00140Q9ZN37-26112 - 2739248423.2
isocitrate dehydrogenase (nadp(+))APV63_RS00145Q9ZN36+27591 - 2886847462.8
duf1523 family proteinAPV63_RS00150P43999+28936 - 2946320224.7

Displaying genes 21 – 30 of 1556 in total

Pathways

26 pathways

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0003949UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-uloseC17H25N3O16P2Chemical structure of UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-uloseNot available
Average589.3384Da
Monoisotopic589.0710048Da
BASm0003971heme bC34H30FeN4O4Not available14875-96-8
Average614.484Da
Monoisotopic614.162739Da
BASm0003983di-trans,octa-cis-undecaprenyl phosphateC55H89O4PChemical structure of di-trans,octa-cis-undecaprenyl phosphateNot available
Average845.288Da
Monoisotopic844.6509455Da
BASm0004092UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineC41H61N9O28P2Chemical structure of UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineNot available
Average1189.924Da
Monoisotopic1189.312320676Da
BASm0004093di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineC87H139N7O23P2Chemical structure of di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineNot available
Average1713.045Da
Monoisotopic1711.941952079Da
BASm0004122ADP-L-glycero-beta-D-manno-heptoseC17H25N5O16P2Chemical structure of ADP-L-glycero-beta-D-manno-heptoseNot available
Average617.355Da
Monoisotopic617.078250901Da
BASm0004172(R)-4'-phosphopantetheineC11H21N2O7PSChemical structure of (R)-4'-phosphopantetheineNot available
Average356.33Da
Monoisotopic356.081806356Da
BASm0004259UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronateC17H20N3O18P2Chemical structure of UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronateNot available
Average616.299Da
Monoisotopic616.023355552Da
BASm0004386N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphateC63H103NO12P2Chemical structure of N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphateNot available
Average1128.461Da
Monoisotopic1127.696649Da
BASm0004431pseudaminateC13H21N2O8Chemical structure of pseudaminateNot available
Average333.318Da
Monoisotopic333.1303392Da

Displaying 51–60 of 94 metabolites