Helicobacter pylori str. 22343

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22343 is a Gram-negative bacterium characterized by its unique spirilla shape and single-cell arrangement. This microbe thrives optimally at a temperature of 37.0°C, which aligns with its adaptation to a host-associated habitat, typically residing in the gastric mucosa of mammals. H. pylori strain 22343 exhibits microaerophilic characteristics, indicating that it requires lower levels of oxygen than are present in the atmosphere for optimal growth. The microaerophilic nature of H. pylori suggests that it is well-adapted to the gastric environment, where oxygen levels are significantly reduced compared to ambient conditions. This adaptation plays a crucial role in its survival and potential interaction with the host's immune system. Understanding the specific growth conditions and environmental preferences of H. pylori strain 22343 can provide insights into its ecological niche within the host and its potential influence on gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22343

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22343
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22343 scaffold_99, whole genome shotgun

Gene Summary

Adenine Count

535227 bp

Thymine Count

539188 bp

Guanine Count

344275 bp

Cytosine Count

341653 bp

Genome Length

1760343 bp

Protein-coding Genes

1534 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
16s ribosomal rnaNot AvailableNot AvailablePositive504 - 2013Not Available
hypothetical proteinBB414_00005Not AvailableNegative1 - 165459346.2
tonb system transport protein exbdBB414_00015Not AvailableNegative2357 - 274614378.4
tonb-system energizer exbbBB414_00020Not AvailableNegative2743 - 318015832.0
nickel responsive regulatorBB414_00025Not AvailablePositive3504 - 395017011.2
nicotinate (nicotinamide) nucleotide adenylyltransferaseBB414_00030Not AvailablePositive3943 - 445819539.1
molecular chaperone dnajBB414_00035Not AvailableNegative4455 - 521629947.6
trna 2-thiouridine(34) synthase mnmaBB414_00040Not AvailablePositive5356 - 638438274.7
hypothetical proteinBB414_00045Not AvailableNegative6425 - 755543888.0
molecular chaperone dnajBB414_00050Not AvailablePositive7680 - 878941942.9

Displaying genes 1 – 10 of 1576 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
CancerCausesPMC7459201
CancerCausesPMC8032737
GastritisCausesPMC8032737
Gastric ulcerCausesPMC8032737
Duodenal ulcerCausesPMC8032737
Gastric cancerCausesPMC8882093
Chronic gastritisCausesPMC8882093
Atrophic gastritisCausesPMC8882093
Intestinal metaplasiaCausesPMC8882093
DysplasiaCausesPMC8882093

Displaying health effects 41 – 50 of 94 in total