Helicobacter pylori str. 1846/05

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1846/05 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and solitary cell arrangement. This strain thrives at an optimal temperature of 37.0°C, which aligns with the physiological conditions of a mammalian host, suggesting its adaptation to a host-associated habitat. H. pylori is known for its ability to colonize the gastric mucosa, where it can influence local microbial communities and interact with host immune responses. The microaerophilic nature of this strain indicates a preference for environments with reduced oxygen levels, which is consistent with its niche in the stomach, where oxygen availability is limited. This adaptation may play a crucial role in its survival and persistence in such a hostile environment, allowing it to evade immune detection. Understanding the specific traits of H. pylori strain 1846/05 can provide insights into its ecological interactions within the gastric ecosystem. The unique combination of its morphology, oxygen requirements, and optimal growth temperature suggests a finely tuned adaptation to the gastric niche, highlighting the complexity of microbial life and its capacity to thrive in specialized habitats. Further research into this strain may reveal additional insights into its role within the gastric microbiome and its interactions with host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain1846/05

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 1846/05
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 1846/05 Contig58, whole genome shotgun

Gene Summary

Adenine Count

499644 bp

Thymine Count

502517 bp

Guanine Count

322326 bp

Cytosine Count

317342 bp

Genome Length

1642077 bp

Protein-coding Genes

1468 genes

Non-Coding Genes

75 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Jhp1044 mosaic, putative crystallin beta/gamma motif-containing proteinHPY1846_02495Not AvailableNegative514973 - 51733388803.1
AttlNot AvailableNot AvailablePositive516920 - 516932Not Available
Hypothetical proteinHPY1846_02500Not AvailableNegative517399 - 51906063945.6
Dna primaseHPY1846_02505Not AvailableNegative519073 - 52064460644.6
Dna repair proteinHPY1846_02510Not AvailableNegative520641 - 52181045445.6
Hypothetical proteinHPY1846_02515Not AvailableNegative521820 - 52208610651.3
Putative phage replication proteinHPY1846_02520Not AvailableNegative522283 - 52324537810.8
Putative transcriptional regulatorHPY1846_02525Not AvailableNegative523248 - 52355011855.5
Hypothetical proteinHPY1846_02530Not AvailableNegative523552 - 5237678401.28
AttrNot AvailableNot AvailablePositive523636 - 523648Not Available

Displaying genes 1 – 10 of 1547 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
CancerCausesPMC4433339
Chronic gastritisCausesPMC8760755
Peptic ulcersCausesPMC8760755
Gastric cancerCausesPMC9093563

Displaying health effects 91 – 94 of 94 in total