Helicobacter pylori str. 1198/04

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1198/04 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical human body temperature, suggesting its adaptation to a host-associated habitat. H. pylori is primarily known for colonizing the gastric epithelium, where it is believed to play a role in various gastrointestinal disorders. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its ecological niche within the acidic environment of the stomach. This adaptation not only enables the bacterium to survive but also allows it to exploit the unique conditions present in the gastric milieu, where it can evade the host's immune responses and establish colonization. Given these traits, H. pylori strain 1198/04 exemplifies the specialized adaptations of bacteria to their host environments, highlighting the intricate relationships between microbial life and host physiology. Such adaptations may influence microbial diversity and stability within the gastrointestinal tract, potentially affecting overall host health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 1198/04

Accession NumberJSXT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1485 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+50 - 167Not Available
23s ribosomal rnaNot AvailableNot Available+405 - 3294Not Available
ribonuclease nHPY1198_00005Not Available-246 - 112434668.8
biotin synthaseHPY1198_00010Not Available-1124 - 197231462.7
restriction endonucleaseHPY1198_00015Not Available+2390 - 473291865.1
restriction endonucleaseHPY1198_00020Not Available+4726 - 658871541.8
16s ribosomal rnaNot AvailableNot Available+6451 - 7960Not Available
endonucleaseHPY1198_00025Not Available+6713 - 757633621.6
hypothetical proteinHPY1198_00030Not Available-7649 - 78256426.87
prephenate dehydrogenaseHPY1198_00035Not Available-7918 - 874530494.4

Displaying genes 1 – 10 of 1526 in total

Pathways

26 pathways

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm0004066di-trans,octa-cis-undecaprenolC55H90OChemical structure of di-trans,octa-cis-undecaprenolNot available
Average767.324Da
Monoisotopic766.6991675Da
BASm00040892'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoAC26H40N7O26P5SChemical structure of 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoANot available
Average1053.56Da
Monoisotopic1053.046472079Da
BASm0004092UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineC41H61N9O28P2Chemical structure of UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineNot available
Average1189.924Da
Monoisotopic1189.312320676Da
BASm0004102dATPC10H12N5O12P3Chemical structure of dATP1927-31-7
Average487.152Da
Monoisotopic486.97172616Da
BASm0004172(R)-4'-phosphopantetheineC11H21N2O7PSChemical structure of (R)-4'-phosphopantetheineNot available
Average356.33Da
Monoisotopic356.081806356Da
BASm0004229CoA-disulfideC42H62N14O32P6S2Chemical structure of CoA-disulfideNot available
Average1524.99Da
Monoisotopic1524.156559Da
BASm000435115-cis-4,4'-diapophytoeneC30H48Chemical structure of 15-cis-4,4'-diapophytoeneNot available
Average408.714Da
Monoisotopic408.375601546Da
BASm0004354all-trans-4,4'-diaponeurosporeneC30H42Chemical structure of all-trans-4,4'-diaponeurosporeneNot available
Average402.666Da
Monoisotopic402.328651352Da
BASm0004386N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphateC63H103NO12P2Chemical structure of N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphateNot available
Average1128.461Da
Monoisotopic1127.696649Da
BASm0004491(1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oateC19H23O6Chemical structure of (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oateNot available
Average347.388Da
Monoisotopic347.150012Da

Displaying 81–90 of 135 metabolites