Helicobacter pylori str. 1198/04

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1198/04 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical human body temperature, suggesting its adaptation to a host-associated habitat. H. pylori is primarily known for colonizing the gastric epithelium, where it is believed to play a role in various gastrointestinal disorders. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its ecological niche within the acidic environment of the stomach. This adaptation not only enables the bacterium to survive but also allows it to exploit the unique conditions present in the gastric milieu, where it can evade the host's immune responses and establish colonization. Given these traits, H. pylori strain 1198/04 exemplifies the specialized adaptations of bacteria to their host environments, highlighting the intricate relationships between microbial life and host physiology. Such adaptations may influence microbial diversity and stability within the gastrointestinal tract, potentially affecting overall host health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 1198/04

Accession NumberJSXT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1485 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+50 - 167Not Available
23s ribosomal rnaNot AvailableNot Available+405 - 3294Not Available
ribonuclease nHPY1198_00005Not Available-246 - 112434668.8
biotin synthaseHPY1198_00010Not Available-1124 - 197231462.7
restriction endonucleaseHPY1198_00015Not Available+2390 - 473291865.1
restriction endonucleaseHPY1198_00020Not Available+4726 - 658871541.8
16s ribosomal rnaNot AvailableNot Available+6451 - 7960Not Available
endonucleaseHPY1198_00025Not Available+6713 - 757633621.6
hypothetical proteinHPY1198_00030Not Available-7649 - 78256426.87
prephenate dehydrogenaseHPY1198_00035Not Available-7918 - 874530494.4

Displaying genes 1 – 10 of 1526 in total

Pathways

26 pathways

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm0005184dihydrourocanateC6H7N2O2Chemical structure of dihydrourocanateNot available
Average139.135Da
Monoisotopic139.051301053Da
BASm0005360N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphateC63H103NO12P2Chemical structure of N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphateNot available
Average1128.461Da
Monoisotopic1127.696648916Da
BASm00057222-amino-2-deoxy-D-gluconate 6-phosphateC6H12NO9PChemical structure of 2-amino-2-deoxy-D-gluconate 6-phosphateNot available
Average273.135Da
Monoisotopic273.0260651Da
BASm0005774alpha-D-glucosamine 6-phosphateC6H13NO8PNot available3616-42-0
Average258.143Da
Monoisotopic258.038426961Da
BASm0006855(R)-lipoateC8H14O2S2Chemical structure of (R)-lipoate1200-22-2
Average206.326Da
Monoisotopic206.0435211Da
BASm0007001UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamateC28H39N5O23P2Chemical structure of UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamateNot available
Average875.582Da
Monoisotopic875.1533009Da
BASm0007003UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioateC35H51N7O26P2Chemical structure of UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioateNot available
Average1047.7583Da
Monoisotopic1047.235898Da
BASm0007089L-anticapsinC9H13NO4Chemical structure of L-anticapsinNot available
Average199.206Da
Monoisotopic199.0844579Da
BASm0007104L-dihydroanticapsinC9H15NO4Chemical structure of L-dihydroanticapsinNot available
Average201.222Da
Monoisotopic201.100108Da
BASm0007337D-allo-isoleucineC6H13NO2Chemical structure of D-allo-isoleucineNot available
Average131.175Da
Monoisotopic131.0946287Da

Displaying 101–110 of 135 metabolites