Helicobacter pylori str. 1198/04

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1198/04 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical human body temperature, suggesting its adaptation to a host-associated habitat. H. pylori is primarily known for colonizing the gastric epithelium, where it is believed to play a role in various gastrointestinal disorders. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its ecological niche within the acidic environment of the stomach. This adaptation not only enables the bacterium to survive but also allows it to exploit the unique conditions present in the gastric milieu, where it can evade the host's immune responses and establish colonization. Given these traits, H. pylori strain 1198/04 exemplifies the specialized adaptations of bacteria to their host environments, highlighting the intricate relationships between microbial life and host physiology. Such adaptations may influence microbial diversity and stability within the gastrointestinal tract, potentially affecting overall host health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 1198/04

Accession NumberJSXT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1485 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
lon proteaseHPY1198_00040Not Available-8754 - 1128895224.9
competence protein comlHPY1198_00045Not Available-11331 - 1199326235.8
flagellar assembly protein fliwHPY1198_00050Not Available+12396 - 1278514833.3
3-hydroxyacyl-acp dehydrataseHPY1198_00055Not Available+12966 - 1344518197.3
Ncrna_class:rnase_p_rnaNot AvailableNot Available+13074 - 13389Not Available
udp-n-acetylglucosamine acyltransferaseHPY1198_00060Not Available+13448 - 1426029857.2
clp protease clpxHPY1198_00065Not Available+14262 - 1560850637.6
rod shape-determining protein mrebHPY1198_00070Not Available+15651 - 1669437341.9
rod shape-determining protein mrecHPY1198_00075Not Available+16698 - 1744428003.9
restriction endonuclease subunit rHPY1198_00080Not Available-17495 - 20386113236.0

Displaying genes 11 – 20 of 1526 in total

Pathways

26 pathways

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm00044923-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoateC13H17O4Chemical structure of 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoateNot available
Average237.276Da
Monoisotopic237.1132326Da
BASm0004493(2Z,4Z)-2-hydroxyhexa-2,4-dienoateC6H7O3Chemical structure of (2Z,4Z)-2-hydroxyhexa-2,4-dienoateNot available
Average127.12Da
Monoisotopic127.0400677Da
BASm0004531(6S)-NADHXC21H29N7O15P2Chemical structure of (6S)-NADHXNot available
Average681.446Da
Monoisotopic681.1207844Da
BASm0004533(6S)-NADPHXC21H28N7O18P3Chemical structure of (6S)-NADPHXNot available
Average759.409Da
Monoisotopic759.0725624Da
BASm0004875Fe-coproporphyrin IIIC36H32FeN4O8Not availableNot available
Average704.519Da
Monoisotopic704.159144Da
BASm0004885UDP-N-acetyl-alpha-D-mannosamineC17H25N3O17P2Chemical structure of UDP-N-acetyl-alpha-D-mannosamineNot available
Average605.34Da
Monoisotopic605.067017513Da
BASm0004925UDP-N-acetyl-alpha-D-muramateC20H28N3O19P2Chemical structure of UDP-N-acetyl-alpha-D-muramateNot available
Average676.395Da
Monoisotopic676.080870429Da
BASm0004926UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanineC40H62N9O26P2Chemical structure of UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanineNot available
Average1146.922Da
Monoisotopic1146.329767888Da
BASm00050533',3'-c-di-AMPC20H22N10O12P2Chemical structure of 3',3'-c-di-AMPNot available
Average656.403Da
Monoisotopic656.0904873Da
BASm00050742-(4-dimethylaminophenyl)diazenylbenzoateC15H14N3O2Chemical structure of 2-(4-dimethylaminophenyl)diazenylbenzoateNot available
Average268.297Da
Monoisotopic268.109150283Da

Displaying 91–100 of 135 metabolites