Helicobacter pylori str. 1198/04

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1198/04 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical human body temperature, suggesting its adaptation to a host-associated habitat. H. pylori is primarily known for colonizing the gastric epithelium, where it is believed to play a role in various gastrointestinal disorders. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its ecological niche within the acidic environment of the stomach. This adaptation not only enables the bacterium to survive but also allows it to exploit the unique conditions present in the gastric milieu, where it can evade the host's immune responses and establish colonization. Given these traits, H. pylori strain 1198/04 exemplifies the specialized adaptations of bacteria to their host environments, highlighting the intricate relationships between microbial life and host physiology. Such adaptations may influence microbial diversity and stability within the gastrointestinal tract, potentially affecting overall host health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 1198/04

Accession NumberJSXT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1485 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
cag pathogenicity island proteinHPY1198_07915Not Available-1608965 - 160962124686.3
cag pathogenicity island proteinHPY1198_07920Not Available+1610001 - 161075929097.4
cag pathogenicity island proteinHPY1198_07925Not Available+1610764 - 161237157755.5
sodium:calcium antiporterHPY1198_07930Not Available+1612424 - 161398960632.7
c4-dicarboxylate abc transporterHPY1198_07940Not Available-1616164 - 161742344725.0
membrane proteinHPY1198_07945Not Available+1617424 - 161833834467.0

Displaying genes 1521 – 1526 of 1526 in total

Pathways

26 pathways

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm0002026acrylateC3H3O2Chemical structure of acrylate10344-93-1
Average71.056Da
Monoisotopic71.013852917Da
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da
BASm0002131(3S)-hydroxy-3-methylglutaryl-CoAC27H39N7O20P3SChemical structure of (3S)-hydroxy-3-methylglutaryl-CoANot available
Average906.62Da
Monoisotopic906.1183419Da
BASm0002198beta-D-ribofuranoseC5H10O5Chemical structure of beta-D-ribofuranose50-69-1
Average150.1299Da
Monoisotopic150.05282343Da
BASm0002665prostaglandin F2alphaC20H33O5Chemical structure of prostaglandin F2alpha0551-11-1
Average353.48Da
Monoisotopic353.2333477Da
BASm0002666prostaglandin H2C20H31O5Chemical structure of prostaglandin H242935-17-1
Average351.464Da
Monoisotopic351.2176977Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm0002749ADP-alpha-D-glucoseC16H23N5O15P2Chemical structure of ADP-alpha-D-glucoseNot available
Average587.329Da
Monoisotopic587.0676862Da
BASm0002759dTDP-beta-L-rhamnoseC16H24N2O15P2Not availableNot available
Average546.316Da
Monoisotopic546.066289237Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da

Displaying 31–40 of 135 metabolites