Helicobacter pylori str. 1198/04

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1198/04 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical human body temperature, suggesting its adaptation to a host-associated habitat. H. pylori is primarily known for colonizing the gastric epithelium, where it is believed to play a role in various gastrointestinal disorders. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its ecological niche within the acidic environment of the stomach. This adaptation not only enables the bacterium to survive but also allows it to exploit the unique conditions present in the gastric milieu, where it can evade the host's immune responses and establish colonization. Given these traits, H. pylori strain 1198/04 exemplifies the specialized adaptations of bacteria to their host environments, highlighting the intricate relationships between microbial life and host physiology. Such adaptations may influence microbial diversity and stability within the gastrointestinal tract, potentially affecting overall host health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 1198/04

Accession NumberJSXT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1485 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+50 - 167Not Available
23s ribosomal rnaNot AvailableNot Available+405 - 3294Not Available
ribonuclease nHPY1198_00005Not Available-246 - 112434668.8
biotin synthaseHPY1198_00010Not Available-1124 - 197231462.7
restriction endonucleaseHPY1198_00015Not Available+2390 - 473291865.1
restriction endonucleaseHPY1198_00020Not Available+4726 - 658871541.8
16s ribosomal rnaNot AvailableNot Available+6451 - 7960Not Available
endonucleaseHPY1198_00025Not Available+6713 - 757633621.6
hypothetical proteinHPY1198_00030Not Available-7649 - 78256426.87
prephenate dehydrogenaseHPY1198_00035Not Available-7918 - 874530494.4

Displaying genes 1 – 10 of 1526 in total

Pathways

26 pathways

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da

Displaying 1–10 of 135 metabolites