Haemophilus influenzae Rd KW20

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus influenzae Rd KW20 is a Gram-negative, rod-shaped bacterium that thrives optimally at a temperature of 35-37 °C. As a chemoheterotroph, it derives its energy from organic compounds, relying on the organic matter present in its environment for growth. This microbe is primarily found in the human respiratory tract, specifically in the nasopharynx and can also be isolated from various other body sites, including the ears, lungs, and sinuses. Classified as a facultative anaerobe, it can live in both aerobic and anaerobic conditions, making it adaptable to a range of environments within the host. H. influenzae Rd KW20 is notable for its role in human health; while it is part of the normal flora of the upper respiratory tract in healthy individuals, it can become pathogenic under certain circumstances. It is known to cause a range of infections, including pneumonia, sinusitis, and otitis media, particularly in children and immunocompromised adults.As a strain in the study of bacterial genetics, H. influenzae Rd KW20 has contributed to significant advancements in the understanding of molecular biology and genetics. Remarkably, it was one of the first organisms to have its genome completely sequenced, providing valuable insights into bacterial evolution, pathogenic mechanisms, and antibiotic resistance. Moreover, its relatively simple genetic makeup makes it an ideal model organism for laboratory studies, facilitating research in areas such as gene expression, protein function, and microbial interactions within the host.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus influenzae
StrainRd KW20

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus influenzae Rd KW20
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Haemophilus influenzae Rd KW20

Accession NumberNC_000907.1

Gene Summary

Adenine Count

567623 bp

Thymine Count

564241 bp

Guanine Count

347436 bp

Cytosine Count

350723 bp

Genome Length

1830138 bp

Protein-coding Genes

1663 genes

Non-Coding Genes

140 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Tail tube proteinHI_RS07795P44234+1582885 - 158324112911.3
Hypothetical proteinHI_RS07800P44235+1583254 - 158363713978.8
Tail assembly proteinHI_RS07805P44236+1583718 - 158561366211.6
Tail/dna circulation proteinHI_RS07810P71389+1585613 - 158698050844.5
Putative tail proteinHI_RS07815P08558+1586980 - 158776528465.6
phage tail proteinHI_RS07820Not Available+1587765 - 158824017359.6
Putative baseplate assembly proteinHI_RS07825P44238+1588277 - 158882519775.4
Putative tail proteinHI_RS07830P44239+1588834 - 158924114965.7
Baseplate j like proteinHI_RS07835P44240+1589241 - 159030838454.0
Hypothetical proteinHI_RS07840P44241+1590334 - 159090021995.6

Displaying genes 61 – 70 of 3606 in total

Pathways

25 pathways

Metabolites

188 records
Metabolite IDMetabolite nameStructureCAS number
BASm0031900LPA(16:1(9Z)/0:0)C19H37O7PChemical structure of LPA(16:1(9Z)/0:0)NULL
Average408.472Da
Monoisotopic408.227690529Da
BASm0032019PA(12:0/14:0)C29H57O8PChemical structure of PA(12:0/14:0)NULL
Average564.7318Da
Monoisotopic564.379105312Da
BASm0032039PA(12:0/18:1(11Z))C33H63O8PChemical structure of PA(12:0/18:1(11Z))NULL
Average618.833Da
Monoisotopic618.426055987Da
BASm0032069PA(14:0/16:0)C33H65O8PChemical structure of PA(14:0/16:0)NULL
Average620.849Da
Monoisotopic620.441706051Da
BASm0032089PA(14:0/18:1(11Z))C35H67O8PChemical structure of PA(14:0/18:1(11Z))NULL
Average646.887Da
Monoisotopic646.457356115Da
BASm0033987PS(12:0/14:0)C32H62NO10PChemical structure of PS(12:0/14:0)NULL
Average651.819Da
Monoisotopic651.411134198Da
BASm0033995PS(12:0/18:1(11Z))C36H68NO10PChemical structure of PS(12:0/18:1(11Z))NULL
Average705.911Da
Monoisotopic705.458084392Da
BASm0034613Palmitoleyl-CoAC37H64N7O17P3SChemical structure of Palmitoleyl-CoA18198-76-0
Average1003.93Da
Monoisotopic1003.329225797Da

Displaying 181–188 of 188 metabolites