Haemophilus influenzae Rd KW20

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus influenzae Rd KW20 is a Gram-negative, rod-shaped bacterium that thrives optimally at a temperature of 35-37 °C. As a chemoheterotroph, it derives its energy from organic compounds, relying on the organic matter present in its environment for growth. This microbe is primarily found in the human respiratory tract, specifically in the nasopharynx and can also be isolated from various other body sites, including the ears, lungs, and sinuses. Classified as a facultative anaerobe, it can live in both aerobic and anaerobic conditions, making it adaptable to a range of environments within the host. H. influenzae Rd KW20 is notable for its role in human health; while it is part of the normal flora of the upper respiratory tract in healthy individuals, it can become pathogenic under certain circumstances. It is known to cause a range of infections, including pneumonia, sinusitis, and otitis media, particularly in children and immunocompromised adults.As a strain in the study of bacterial genetics, H. influenzae Rd KW20 has contributed to significant advancements in the understanding of molecular biology and genetics. Remarkably, it was one of the first organisms to have its genome completely sequenced, providing valuable insights into bacterial evolution, pathogenic mechanisms, and antibiotic resistance. Moreover, its relatively simple genetic makeup makes it an ideal model organism for laboratory studies, facilitating research in areas such as gene expression, protein function, and microbial interactions within the host.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus influenzae
StrainRd KW20

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus influenzae Rd KW20
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Haemophilus influenzae Rd KW20

Accession NumberNC_000907.1

Gene Summary

Adenine Count

567623 bp

Thymine Count

564241 bp

Guanine Count

347436 bp

Cytosine Count

350723 bp

Genome Length

1830138 bp

Protein-coding Genes

1663 genes

Non-Coding Genes

140 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Portal proteinHI_RS07745P44225+1574062 - 157562458372.4
Virion morphogenesis late f orfHI_RS07750P44226+1575715 - 157695946497.2
Putative virion morphogenesis proteinHI_RS07755O05072+1577097 - 157753716410.5
Putative protease proteinHI_RS07760O05073+1577768 - 157883539028.2
Major head proteinHI_RS07765P44227+1578835 - 157976133813.0
hypothetical proteinHI_RS07770P44228+1579844 - 158022914184.2
Hypothetical proteinHI_RS07775P44230+1580235 - 158065715774.6
Hypothetical proteinHI_RS07780P44231+1580657 - 158120820494.2
duf2635 domain-containing proteinHI_RS07785P44232+1581221 - 15814127161.52
Tail sheath proteinHI_RS07790P44233+1581412 - 158287553146.5

Displaying genes 51 – 60 of 3606 in total

Pathways

25 pathways

Metabolites

188 records
Metabolite IDMetabolite nameStructureCAS number
BASm00189052-Acyl-sn-glycero-3-phosphoglycerol (N-C18:0)C24H48O9PChemical structure of 2-Acyl-sn-glycero-3-phosphoglycerol (N-C18:0)NULL
Average511.6063Da
Monoisotopic511.303594646Da
BASm00189062-Acyl-sn-glycero-3-phosphoglycerol (N-C18:1)C24H46O9PChemical structure of 2-Acyl-sn-glycero-3-phosphoglycerol (N-C18:1)NULL
Average509.5904Da
Monoisotopic509.287944582Da
BASm00189092-dodecanoyl-sn-glycerol 3-phosphateC15H31O7PChemical structure of 2-dodecanoyl-sn-glycerol 3-phosphateNULL
Average354.3762Da
Monoisotopic354.180739858Da
BASm00189102-hexadec-9-enoyl-sn-glycerol 3-phosphateC19H37O7PNot availableNULL
Average408.472Da
Monoisotopic408.227690529Da
BASm00189112-hexadecanoyl-sn-glycerol 3-phosphateC19H39O7PNot availableNULL
Average410.488Da
Monoisotopic410.243340594Da
BASm00189122-octadec-11-enoyl-sn-glycerol 3-phosphateC21H41O7PNot availableNULL
Average436.526Da
Monoisotopic436.258990658Da
BASm00189132-octadecanoyl-sn-glycerol 3-phosphateC21H43O7PChemical structure of 2-octadecanoyl-sn-glycerol 3-phosphateNULL
Average438.5357Da
Monoisotopic438.274640242Da
BASm00189142-tetradec-7-enoyl-sn-glycerol 3-phosphateC17H33O7PChemical structure of 2-tetradec-7-enoyl-sn-glycerol 3-phosphateNULL
Average380.4135Da
Monoisotopic380.196389922Da
BASm00189152-tetradecanoyl-sn-glycerol 3-phosphateC17H35O7PChemical structure of 2-tetradecanoyl-sn-glycerol 3-phosphateNULL
Average382.4294Da
Monoisotopic382.212039986Da
BASm0019191PE(16:1(9Z)/18:1(9Z))C39H74NO8PChemical structure of PE(16:1(9Z)/18:1(9Z))NULL
Average715.994Da
Monoisotopic715.515205345Da

Displaying 151–160 of 188 metabolites